Related Experiment Video

Updated: Jun 27, 2026

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
07:45

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis

Published on: February 9, 2021

Hypercalciuria and recurrent urinary tract infections among children in Zahedan, Iran

Simin Sadeghi-Bojd1, Mohammad Hashemi

  • 1Department of Pediatrics, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

JPMA. the Journal of the Pakistan Medical Association
|November 26, 2008
PubMed

Insights

Idiopathic urinary tract infection (UTI) is linked to higher urinary calcium levels in children. This study found hypercalciuria more common in children with UTI, especially females, suggesting calcium evaluation is important.

Area of Science:

  • Pediatric Nephrology
  • Urology
  • Clinical Biochemistry

Background:

  • Recurrent urinary tract infections (UTIs) are a common pediatric concern.
  • Hypercalciuria, elevated calcium in urine, is a potential risk factor for UTIs.

Purpose of the Study:

  • To investigate the association between idiopathic urinary tract infections and hypercalciuria in Iranian children.
  • To determine if urinary calcium levels are elevated in children experiencing UTIs.

Main Methods:

  • A case-control study involving 70 children with UTI episodes and 70 healthy controls.
  • Measurement of random urine calcium-creatinine ratio (UCa/Cr) and plasma calcium levels in all participants.

Main Results:

  • Hypercalciuria was significantly more prevalent in children with UTI (30%) compared to healthy controls (11.4%).
  • The frequency of hypercalciuria was notably higher in female UTI patients (42.9%) than in males (17.1%).

Conclusions:

  • Elevated urinary calcium excretion is associated with idiopathic UTIs in pediatric populations.
  • Investigating urinary calcium levels is recommended for children with recurrent UTIs to identify potential underlying causes.
Abstract

More Related Videos

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Related Concept Videos

Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...