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Cervical stump carcinoma.

J J Kovalic1, P W Grigsby, C A Perez

  • 1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.

International Journal of Radiation Oncology, Biology, Physics
|May 1, 1991
PubMed
Summary
This summary is machine-generated.

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Cancer in the cervical stump, a rare occurrence after supracervical hysterectomy, can be effectively treated with radiation therapy. Outcomes for cervical stump cancer are comparable to those for intact cervix cancer.

Area of Science:

  • Gynecologic Oncology
  • Radiation Oncology
  • Oncology

Background:

  • Supracervical hysterectomy leaves a cervical stump, which can develop cancer years later.
  • Cancer of the cervical stump is a rare but significant clinical entity.

Purpose of the Study:

  • To evaluate the treatment outcomes and survival rates for patients diagnosed with carcinoma of the cervical stump.
  • To compare outcomes of cervical stump cancer with those of cervical cancer in patients with an intact uterus.

Main Methods:

  • Retrospective review of 70 patients treated for cervical stump carcinoma.
  • Treatment modalities included external beam radiation and/or intracavitary implants, with some patients undergoing surgery.
  • Analysis of overall survival, progression-free survival, and prognostic factors.

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Main Results:

  • The 5- and 10-year overall survival rates were 60% and 40%, respectively.
  • Progression-free survival at 5 and 10 years was 77% and 70%, respectively.
  • Poor histologic differentiation, Black race, and prolonged external beam irradiation were associated with worse prognosis.

Conclusions:

  • Radiation therapy provides effective treatment for carcinoma of the cervical stump.
  • Outcomes for treated cervical stump cancer are comparable to those for cervical cancer in patients with an intact uterus.
  • Cervical stump cancer patients are diagnosed at an older median age and often years after hysterectomy.