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Updated: Jun 27, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
Published on: July 1, 2018
[Streptococcus suis meningitis in an immunocompetent patient]
A Nagel1, V Manias, N Busquets
1Sección Microbiología, Laboratorio Central, Hospital José M. Cullen, Av. Freyre 2150 (3000) Santa Fe, Pcia. de Santa Fe, Argentina
This case study details Streptococcus suis meningitis in an immunocompetent patient. Early diagnosis and treatment are crucial, as the infection can lead to severe neurological complications like hearing loss and ataxia.
Area of Science:
- Infectious Diseases
- Bacteriology
- Neurology
Background:
- Streptococcus suis is an emerging zoonotic pathogen.
- Meningitis can present with diverse neurological symptoms.
Observation:
- An immunocompetent patient developed meningitis with symptoms including fever, vomiting, and neurological deficits.
- Cerebrospinal fluid and blood cultures confirmed Streptococcus suis infection.
Findings:
- The Streptococcus suis isolate was susceptible to ampicillin, ceftriaxone, cefotaxime, and vancomycin.
- Initial treatment led to clinical improvement but was followed by progressive hearing loss and ataxia.
Implications:
- This case highlights the importance of considering Streptococcus suis in meningitis, especially with potential pig exposure.
- Prompt identification and appropriate antimicrobial therapy are essential to prevent severe sequelae.
- Further investigation into predisposing and epidemiological factors is vital for early detection and management.
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