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Updated: Jun 27, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
Published on: April 8, 2013
[Diastolic heart failure: myth or fact?]
Letizia Conti1, René Lerch, Arnaud Perrier
1Service de médecine interne générale, HUG, 1211 Genève 14. letizia.conti@hcuge.ch
Insights
Heart failure with preserved ejection fraction (HFpEF), previously diastolic heart failure, is diagnosed non-invasively. Treatment focuses on controlling hypertension, heart rate, and fluid overload.
Area of Science:
- Cardiology
- Internal Medicine
Context:
- Diastolic heart failure is a common clinical diagnosis.
- Accurate terminology is now heart failure with preserved ejection fraction (HFpEF).
Purpose:
- To outline current diagnostic and treatment strategies for HFpEF.
- To emphasize key management principles for this condition.
Summary:
- HFpEF can be diagnosed non-invasively using echocardiography and brain natriuretic peptide (BNP) measurements.
- Evidence-based treatment guidelines for HFpEF are less established than for heart failure with reduced ejection fraction.
- Key therapeutic goals include hypertension and heart rate control, alongside diuretic use for fluid overload.
Impact:
- Improved diagnostic accuracy and understanding of HFpEF.
- Highlights the importance of managing comorbidities and symptoms in HFpEF patients.
- Provides a concise overview for clinicians managing patients with HFpEF.
Abstract:
Diastolic heart failure is a frequent diagnosis, but now it is more acurate to call this heart failure with preserved ejection fraction. The diagnosis can be made non invasively by the echocardiography and measuring BNP (brain natriuretic peptide). Consensus about treatment are less evidence-based than for heart failure with diminished ejection fraction. It is however certain that control of hypertension and heart rate are important. Fluid overload must also be treated with diuretics.
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