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Updated: Jun 27, 2026

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
Published on: July 27, 2022
Development of a synthetic bone scaffold using porous hydroxyapatite for bone repair
R Mustaffa1, I Besar, M Andanastuti
1Material Technology Group (MTEG), Industrial Technology Division, Malaysian Nuclear Agency, Bangi, 43000 Kajang, Selangor DE. rusnah_m@nuclearmalaysia.gov.my
Abstract:
In this study, porous hydroxyapatite (HA) samples were fabricated via sponge techniques with the aid of sago as part of the binder mixture. Development processes for the production of porous bone graft substitutes are studied using polyurethane sponge. To obtain the optimum amount of binder for successful fabrication of porous HA were done. Initially, porous HA powder was synthesized using calcium hydroxide and orthorphosphoric acid. Meanwhile, sago was mixed with PVA in a certain ratio to be used as binder for preparing the porous HA. After a series of investigative tests were conducted to characterize the sintered samples, the use of the sago and polymeric mixture was found to successfully aid the fabrication of porous HA samples. In this investigation, comparison of physical and mechanical characteristics between samples prepared using difference techniques was made.
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