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Updated: Jun 27, 2026

Preparation of Food Samples Using Homogenization and Microwave-Assisted Wet Acid Digestion for Multi-Element Determination with ICP-MS
Published on: December 22, 2023
[Development and evaluation of determination methods for boric acid in agar using ICP-AES and ICP-MS]
Megumi Hamano-Nagaoka1, Rieko Matsuda, Tamio Maitani
1National Institute of Health Sciences, 1181 Kamiyoga, Setagaya-ku, Tokyo 1588501, Japan.
Abstract:
A new test method for boric acid in agar was developed. After digestion with nitric acid, the concentration of boron was measured by ICP-AES or ICP-MS with internal standards. Collaborative studies involving 5 laboratories were conducted to evaluate the new method by using a finely powdered agar sample and a standard sample (NIST SRM SRM1570a). The repeatability and reproducibility were very good. Moreover, HORRAT(R) values were less than 2. Therefore, it was considered that the new method is acceptable for the determination of boric acid in agar.
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