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Chaetoglobins A and B, two unusual alkaloids from endophytic Chaetomium globosum culture
Hui Ming Ge1, Wei Yun Zhang, Gang Ding
1Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, PR China.
Abstract:
Chaetoglobins A (1) and B (2), two azaphilone alkaloid dimers with an unprecedented skeleton, were characterized from an endophytic fungus Chaetomium globosum with the former ascertained to be a significant cytotoxin valuable for anti-tumor drug discovery.
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