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Updated: Jun 27, 2026

06:26
Selective Capture of 5-hydroxymethylcytosine from Genomic DNA
Published on: October 5, 2012
Highly selective detection of 5-methylcytosine using photochemical ligation
Masayuki Ogino1, Yuuta Taya, Kenzo Fujimoto
1Japan Science and Technology Agency, Ishikawa, 923-1211, Japan.
Abstract:
We report the nonenzymatic detection of 5-methylcytosine by using template-directed photoligation through 5-cyanovinyl-2'-deoxyuridine ((C)U) with high selectivity and present a new methylation detection method using a photoligation-based DNA chip assay.

