Three-dimensional perfusion imaging of hepatocellular carcinoma using 256-slice multidetector-row computed tomography
Tatsushi Kobayashi1, Takayuki Hayashi, Shintaro Funabasama
1Division of Radiology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, 277-8577, Japan. takobaya@east.ncc.go.jp
Purpose:
The aim of this study was to evaluate the clinical capability of three-dimensional (3D) perfusion imaging of hepatocellular carcinoma (HCC) by performing dynamic scanning using a 256-slice multidetector-row CT (MDCT) scanner.
Materials And Methods:
Two patients with HCC were examined in this study. They were scheduled to undergo transcatheter arterial infusion therapy using an arterial infusion reservoir system. The CT system used was a newly developed prototype scanner of 256-slice MDCT. Dynamic CT scanning was performed with intraarterial injection via the reservoir route, and perfusion analysis was done based on the 3D data.
Results:
The blood flow volume per unit volume in the tumors was significantly increased compared with that in normal hepatic parenchyma. Using a 3D workstation, 3D perfusion images could be displayed by fusing CT images with perfusion images about blood flow volume.
Conclusion:
Three-dimensional perfusion images, which enable 3D evaluation of perfusion in HCCs, can be generated using 256-slice MDCT.
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