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Updated: Jun 11, 2026
08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Clinical Outcomes of First-Time and Redo Mitral Valve Replacement Using MITRIS RESILIA Bioprosthesis
Satoshi Kainuma1, Tomoki Shimokawa2,3, Tomohiro Iwakura2
1Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan.
Annals of Thoracic Surgery Short Reports
|June 10, 2026
Summary
The MITRIS RESILIA bioprosthetic valve shows excellent safety and hemodynamic performance in mitral valve replacement (MVR) for both initial and redo procedures. This study confirms its durability and effectiveness in improving patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Bioprosthetic Heart Valves
- Mitral Valve Replacement
Background:
- The MITRIS RESILIA bioprosthetic valve features anticalcification technology for fragile mitral annuli.
- Limited clinical data exists on the safety and hemodynamic performance of this valve.
Purpose of the Study:
- To evaluate the safety and hemodynamic performance of the MITRIS RESILIA valve in mitral valve replacement (MVR).
- To assess outcomes in both first-time and redo MVR procedures.
Main Methods:
- A retrospective multicenter study included 140 patients undergoing MVR with the MITRIS RESILIA valve.
- Patients underwent either first-time (n=100) or redo (n=40) MVR.
- Mean follow-up was 36 months (415 patient-years).
Main Results:
- Low 30-day mortality (2.0% first-time, 0% redo).
- At 3 years, freedom from mortality, reoperation, stroke, and structural valve deterioration was high (89-100%).
- Favorable and stable hemodynamics, with significant improvements in left atrial size and NYHA functional class.
Conclusions:
- First-time and redo MVR with the MITRIS RESILIA valve demonstrated low perioperative mortality and favorable safety.
- The valve exhibited durable hemodynamic performance, supporting its use in diverse mitral valve disease scenarios.
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