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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
Prospective memory impairment in former users of methamphetamine
Peter G Rendell1, Magdalena Mazur, Julie D Henry
1School of Psychology, Australia Catholic University, 115 Victoria Parade, Fitzroy, Melbourne, Victoria 3065, Australia. peter.rendell@acu.edu.au
Prior methamphetamine use significantly impairs prospective memory, the ability to remember future intentions, even after months of abstinence. These memory deficits affect daily functioning.
Area of Science:
- Neuroscience
- Psychology
Background:
- Methamphetamine use is linked to neurocognitive impairment.
- Previous research has not examined prospective memory deficits in methamphetamine users.
Purpose of the Study:
- To assess prospective memory performance in abstinent methamphetamine users using a simulated real-world task (Virtual Week).
- To investigate the nature of prospective memory failures in this population.
Main Methods:
- Twenty abstinent methamphetamine users and 20 controls completed the Virtual Week task.
- Cognitive functions, including retrospective memory and executive functioning, were also assessed.
Main Results:
- Methamphetamine users showed significant impairments in prospective memory on the Virtual Week task.
- Deficits were generalized and not specific to task demands.
- Cognitive inhibition was strongly associated with prospective memory performance.
Conclusions:
- Prospective memory deficits persist in individuals with a history of methamphetamine use, even during abstinence.
- These generalized prospective memory impairments likely impact daily life functioning.
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