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Updated: Jun 27, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Preparing nurses to initiate thrombolytic therapy for patients with an acute myocardial infarction - is there a
1Principal Lecturer in Critical Care, School of Acute and Critical Care Nursing, Faculty of Health and Social Care, University of the West of England, Glenside Campus, Blackberry Hill, Bristol BS16 1DD, UK.
Abstract:
Within cardiac practice, one area that has seen much development involves the nurse assessing, diagnosing, and prescribing thrombolytic therapy for patients with a myocardial infarction. Alongside this, a variety of titles aimed at defining these new roles have emerged, but instead of clarifying the situation they have created more confusion about the actual characteristics and functions of nurses engaged in these innovative posts. In addition advice regarding the nature of preparation and training required to ensure the competency of nurses for these specific roles has been sparse and inconspicuous. As posts such as 'acute chest pain nurse', 'thrombolysis nurse', 'nurse-initiated thrombolysis' or 'nurse-led thrombolysis' increase and National Health Service targets tighten, it is timely to critically review the educational preparation for these roles for evidence of coherence. In particular, this paper analyses the literature in order to examine the content of educational programmes, teaching methods and assessment strategies in relation to preparing nurses to initiate thrombolytic therapy. The implications for those managing practice and the higher education sector are discussed. Finally, it is stressed that there is a need for national consultation relating to guidelines, standards and accreditation of practice schemes in this area of patient care.
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