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Updated: Jun 27, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

[Management of a ruptured globe].

A Viestenz¹, W Schrader, M Küchle

¹Augenklinik mit Poliklinik der Otto-von-Guericke-Universität, Leipziger Strasse 44, 39120 Magdeburg. arne.viestenz@med.ovgu.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft

|December 2, 2008

Summary

Globe rupture is a severe eye injury that can cause blindness. Prompt diagnosis and immediate, watertight wound closure are crucial to prevent complications like infection and vision loss.

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Area of Science:

Ophthalmology
Trauma Surgery

Context:

Globe rupture is a severe open globe injury with significant risk factors including prior intraocular surgery, myopia, and advanced age.
Differentiating occult globe rupture from severe ocular contusion can be challenging due to significant subconjunctival hemorrhage and swelling.

Purpose:

To highlight the diagnostic challenges and critical management steps for globe rupture following blunt ocular trauma.
To emphasize the importance of timely surgical intervention to prevent severe visual impairment or blindness.

Summary:

Accurate diagnosis of globe rupture requires limbal and scleral exploration after 360-degree peritomy, especially when differentiating from severe contusion.
Immediate and watertight wound closure is essential to prevent complications such as expulsive choroidal hemorrhage, ocular hypotony, and epithelial ingrowth.
Delayed closure increases the risk of posttraumatic endophthalmitis, while early vitrectomy may prevent tractional retinal detachment.

Impact:

Establishes the critical role of prompt surgical management in preserving vision after globe rupture.
Provides guidance on diagnostic approaches and essential surgical techniques for managing severe blunt ocular trauma.
Underscores the potential long-term visual consequences of delayed or inadequate treatment for globe rupture.