Related Experiment Video
Updated: Jun 27, 2026
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Modern methods for cancer external radiation therapies]
Philippe Giraud1, Mehdi Henni, Martin Housset
1Service d'oncologie-radiothérapie, Hôpital européen Georges-Pompidou, 75015 Paris, France. philippe.giraud@egp.aphp.fr
La Revue Du Praticien
|December 3, 2008
Summary
Advancements in radiotherapy utilize modern imaging and planning for precise tumor targeting. New technologies like CyberKnife and tomotherapy offer improved treatment for complex cancers, sparing healthy tissues.
Area of Science:
- Radiation oncology
- Medical physics
- Cancer treatment technologies
Context:
- Radiotherapy has evolved significantly over the last century.
- Modern radiotherapy incorporates advanced imaging, 3D planning, immobilization, and quality assurance.
- Conformal radiotherapy aims to precisely target tumors while minimizing dose to surrounding healthy tissues.
Purpose:
- To review the progress and new technologies in radiotherapy.
- To highlight the benefits of conformal radiotherapy in dose distribution and tumor targeting.
- To introduce advanced systems such as CyberKnife, tomotherapy, and hadrontherapy for complex tumor treatment.
Summary:
- Continuous progress in radiotherapy leverages enhanced imaging, 3D treatment planning, and immobilization techniques.
- Conformal radiotherapy focuses on delivering a high dose to the target volume and reducing exposure to healthy tissues, enabling potential dose escalation.
- Emerging technologies like CyberKnife, tomotherapy, and hadrontherapy show significant promise for treating complex tumors resistant to conventional methods.
Impact:
- Improved precision in radiation delivery for cancer treatment.
- Potential for increased tumor control through dose escalation.
- Enhanced therapeutic options for challenging and complex tumor cases.
Related Concept Videos
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:57Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
01:27Tumor Immunotherapy
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
01:21Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
01:17Radiation: Applications
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
The average...