Related Experiment Video
Updated: Jun 27, 2026

07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Blindness, optic atrophy and sinusitis in the horse
K C Barnett1, A S Blunden, S J Dyson
1Center for Small Animal Studies, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, UK. keith.barnett@aht.org.uk
Veterinary Ophthalmology
|December 17, 2008
Summary
Equine vision loss linked to spheno-palatine sinus infections. Advanced imaging like MRI is crucial for diagnosing optic nerve compression and guiding treatment in horses with visual deficits.
Area of Science:
- Veterinary Ophthalmology
- Equine Neurology
Background:
- Visual deficits in horses can range from blindness to transient disturbances.
- Ocular examination may not reveal abnormalities in cases of optic nerve compromise.
Observation:
- Three horses with varied histories of upper respiratory tract infection presented with visual deficits.
- Specialist veterinary ophthalmological examination provided limited diagnostic value.
Findings:
- Infection of the spheno-palatine sinuses was identified as the common cause.
- Sinus distension led to compression of the optic nerves and optic chiasm.
Implications:
- Magnetic resonance imaging (MRI) and computed tomography (CT) are essential for accurate diagnosis.
- Early diagnosis via advanced imaging facilitates timely and potentially successful treatment.
- Spheno-palatine sinus involvement causing visual disturbances is noted in both equine and human medicine.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Anatomy of the Eyeball
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...

