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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
Gene polymorphisms predisposing to cardiac hypertrophy in patients with cardiac syndrome X
Agata Jabrocka-Hybel1, Władysława Kolasińska-Kloch, Małgorzata Malczewska-Malec
1Colegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
Abstract:
Polymorphisms of the angiotensin-converting enzyme gene and endothelial nitric oxide synthase gene have been suggested to be associated with left ventricular hypertrophy. The aim of our study was to asses the association between above polymorphisms and left ventricular hypertrophy in patients with cardiac syndrome X. The presence of allele 4 of eNOS VNTR polymorphism could predispose to cardiac hypertrophy. The pathological course of postprandial lipemia in patients with CSX may add to the understanding of the CSX pathology.
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