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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Disorders of Erythrocytes

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Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
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Updated: Jun 27, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Anemia in older adults.

Ayhan Aytekin Lash¹, Sharon M Coyer

¹Northern Illinois University, School of Nursing, DeKalb, IL, USA.

Medsurg Nursing : Official Journal of the Academy of Medical-Surgical Nurses

|December 5, 2008

Summary

Anemia in older adults significantly impacts quality of life and increases health risks. This review covers its causes, diagnosis, and management strategies for better patient outcomes.

Area of Science:

Gerontology
Hematology
Internal Medicine

Background:

Anemia is a prevalent condition in older adults, often overlooked.
It is linked to diminished quality of life, cognitive decline, and functional impairment.
Anemia in the elderly increases risks of falls, infections, morbidity, and mortality.

Purpose of the Study:

To review the prevalence, etiology, pathophysiology, and diagnosis of anemia in the older adult population.
To identify collaborative interventions for managing anemia in older adults.

Main Methods:

Literature review of anemia in older adults.
Synthesis of current knowledge on prevalence, causes, and diagnosis.
Identification of management strategies and collaborative approaches.

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Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

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Published on: July 5, 2017

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Last Updated: Jun 27, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Main Results:

Anemia in older adults is associated with significant negative health outcomes.
Understanding the multifaceted causes is crucial for diagnosis.
Effective management requires a collaborative approach involving patients, families, and healthcare providers.

Conclusions:

Anemia poses a serious health challenge for older adults, affecting multiple aspects of well-being.
Comprehensive diagnostic approaches are necessary.
Interdisciplinary collaboration is key to successful anemia management in this demographic.