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Case report: severe, symptomatic hypomagnesemia in acute leptospirosis
Anne Spichler1, Daniel A Athanazio, Juvencio Furtado
1Department of Nephrology, University of São Paulo School of Medicine, and Department of Infectious Diseases, Heliopolis General Hospital, São Paulo, Brazil.
Abstract:
We report a case of severe hypomagnesemia in non-oliguric acute renal failure caused by leptospirosis that required large doses of magnesium replacement during the acute phase of disease. Biochemical studies confirmed kidney-related magnesium wasting and the mechanisms of this defect are discussed. Magnesium imbalance with its attendant clinical complications occurs in leptospirosis and should be monitored and treated aggressively in cases of leptospirosis-induced non-oliguric acute kidney injury.
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