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Construction of fluorescent probes via protection/deprotection of functional groups: a ratiometric fluorescent probe
Weiying Lin1, Lin Yuan, Wen Tan
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan, PR China. weiyinglin@hnu.cn
Abstract:
Herein a ratiometric fluorescent Cu(2+) probe was rationally constructed in a straightforward manner with the concept of aldehyde group protection/deprotection. The probe showed a ratiometric fluorescent response to Cu(2+) with a large emission wavelength shift (>100 nm) and displayed high selectivity for Cu(2+) over other metal ions due to distinct deprotection conditions. In addition, a Cu(2+)-promoted dethioacetalization mechanism was proposed.
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