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Related Concept Videos

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
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Shuttle-based fluorogenic silver-cluster biolabels

Junhua Yu1, Sungmoon Choi, Robert M Dickson

  • 1School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA.

Angewandte Chemie (International Ed. in English)
|December 5, 2008
PubMed
Summary

No abstract available in PubMed .

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