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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
[Prevalence of allergic diseases in the elderly]
Martín Becerril Angeles1, Carlos L Vázquez Merino, Ulises Angeles Garay
1Servicio de Alergia e Inmunología Clínica, Hospital de Especialidades Centro Médico Nacional La Raza, IMSS. mbecer@avantel.net
Background:
A population aged 65 and over has been increasing in many countries, including Mexico. Allergic diseases are common in this age group, asthma prevalence has been reported between 2 and 17% in elderly people. There is no data about allergic diseases prevalence in elderly Mexican people.
Objective:
To know the prevalence of some allergic diseases, allergen sensitization and total IgE serum concentration in a sample of subjects older than 60 years residents in Mexico City.
Patients And Methods:
We included 333 elderly subjects, were included 281 females (84%) and 52 males, with an age-average of 67.2 +/- 5.4, who were attending a social security recreative center. Medical files were made to each one elderly subject, including atopic personal history; skin tests were performed with 10 allergens, histamine and negative controls; and total serum IgE was measured by ELISA. Analysis was made with descriptive statistics, Spearman's coefficient and chi square.
Results:
Allergic diseases were present in 10.8% of the subjects, asthma in 3.6%, allergic rhinitis in 3.6%, urticaria in 2.7%, atopic dermatitis in 0.6% and allergic conjunctivitis in 0.3%, 24% had data of adverse drug reactions and 6.9% referred venom insect hypersensitivity. Skin tests results were positive in 84 subjects (25.2%). In the group of 60-69 years it was observed a significant increase in IgE concentration (p < 0.01), we didn't find a significant correlation between IgE levels and both allergic symptoms and skin tests results.
Conclusions:
The prevalence of allergic diseases, total IgE levels and allergen sensitization in elderly people were similar to studies in other countries, but with a lower pattern than in younger Mexican population.
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