Related Experiment Video
Updated: Jun 27, 2026

Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
Published on: July 6, 2022
The role of the meniscus in osteoarthritis genesis
1Musculoskeletal Sciences, Department of Orthopedics, Lund University, Hs 32, Box 117, SE-221 00 Lund, Sweden. martin.englund@med.lu.se
Abstract:
The history of treating meniscal lesions has been characterized by firm belief in "radical" surgery, with serious long-term consequences for the individual and society. The menisci play a critical protective role for the knee joint through shock absorption and load distribution. Currently, the consensus in surgical treatment of meniscal tears is to preserve as much functional meniscal tissue as possible. Still, meniscal lesions are common, especially in the osteoarthritic knee. For health professionals, these lesions present a challenge in choosing the treatment that is best for the patient in both the short term and long term. A degenerative lesion, in the middle-aged or older patient, could suggest early-stage knee osteoarthritis and should be treated accordingly. Surgical resection of nonobstructive degenerate lesions may only remove evidence of the disorder while the osteoarthritis degradation proceeds. Well-designed randomized, controlled clinical trials are needed.
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...
Degenerative Disc Disease ll: Pathophysiology
Degenerative Disc Disease I: Introduction