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Updated: Jun 27, 2026

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
Published on: April 1, 2019
Pharmacogenetic testing for warfarin sensitivity
Elaine Lyon1, Gwen McMillin, Roberta Melis
1Department of Pathology, University of Utah, Salt Lake City, Utah, USA. lyone@aruplab.com
Abstract:
With the US Food and Drug Administration's recent label change of warfarin to include genetic testing for warfarin sensitivity, manufacturers are developing assays, and laboratories are offering testing. This article describes the genetic variants for which testing is available. Current technologies and assays are compared, including considerations for laboratories in choosing a method. Finally, laboratory issues that apply to all methods, such as quality control and proficiency testing as well as service issues including turn-around-time requirements are discussed.
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