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Related Experiment Video

Updated: Jun 27, 2026

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

Bone cement implantation syndrome.

A J Donaldson¹, H E Thomson, N J Harper

¹Department of Anaesthesia, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK.

British Journal of Anaesthesia

|December 9, 2008

Summary

This summary is machine-generated.

Bone cement implantation syndrome (BCIS) is a serious complication of cemented hip arthroplasty, potentially causing mortality. Identifying high-risk patients allows for surgical selection to minimize BCIS risks.

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Area of Science:

Orthopedic Surgery
Anesthesiology
Critical Care Medicine

Background:

Bone cement implantation syndrome (BCIS) is a poorly understood complication during cemented hip arthroplasty.
BCIS can lead to significant intraoperative mortality and morbidity, and milder postoperative symptoms like hypoxia and confusion.
The increasing prevalence of hip arthroplasty in an aging population, often with comorbidities, heightens the risk of BCIS.

Purpose of the Study:

To review the definition, incidence, clinical features, risk factors, etiology, pathophysiology, risk reduction, and management of BCIS.
To identify patient groups at high risk for developing BCIS.
To provide recommendations for minimizing BCIS-related morbidity and mortality.

Main Methods:

Comprehensive literature review on bone cement implantation syndrome.
Analysis of clinical features, risk factors, and etiological pathways.
Evaluation of current risk reduction strategies and management protocols.

Main Results:

BCIS is a critical factor in intraoperative complications following cemented hip arthroplasty.
Older patients with comorbidities represent a high-risk group for BCIS.
Surgical selection (e.g., uncemented arthroplasty) and invasive anesthetic monitoring in high-risk patients can mitigate risks.

Conclusions:

Early identification of high-risk patients is crucial for preventing BCIS complications.
Tailoring surgical approach and anesthetic management can significantly reduce BCIS-related mortality and morbidity.
Further research into BCIS pathophysiology may improve preventative strategies.