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Related Experiment Video

Updated: Jun 27, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

[Pyodermatitis-pyostomatitis vegetans with nasal involvement].

L Peuvrel1, S Barbarot, V Gagey-Caron

  • 1Service de dermatologie, CHU de Nantes, Hôtel Dieu, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France.

Annales De Dermatologie Et De Venereologie
|December 9, 2008
PubMed
Summary
This summary is machine-generated.

Pyodermatitis-pyostomatitis vegetans (PPV) is a rare condition. This case highlights isolated oral, labial, and nasal mucosal lesions, emphasizing the need for broader diagnostic considerations in PPV.

Related Experiment Videos

Last Updated: Jun 27, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Area of Science:

  • Dermatology
  • Gastroenterology
  • Oral Medicine

Background:

  • Pyodermatitis-pyostomatitis vegetans (PPV) is a rare chronic disorder.
  • PPV is typically associated with inflammatory bowel disease (IBD), most commonly ulcerative colitis.
  • Oral mucosal lesions are a hallmark of PPV.

Observation:

  • A 28-year-old man presented with a 2-year history of painless stomatitis.
  • Examination revealed pustular and exophytic lesions on the oral mucosa, lower lip, and nostrils.
  • Histopathology showed epithelial hyperplasia, suprabasal cleft, acantholysis, neutrophils, and eosinophils.

Findings:

  • The patient had no associated bowel disease, presenting an isolated case of PPV.
  • Direct and indirect immunofluorescence assays were negative.
  • Lesions resolved with oral corticosteroids but demonstrated steroid dependency.

Implications:

  • This case expands the clinical presentation of PPV to include isolated intranasal lesions.
  • The findings suggest PPV can occur without underlying IBD, particularly in younger individuals.
  • Steroid dependency highlights the chronic nature and management challenges of PPV.