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Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

Skin Diseases and Disorders

Skin Diseases and Disorders

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Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

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Reticular Dermis

Reticular Dermis

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Reticular Layer
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Rheumatic Heart Disease I: Introduction

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

Elastin is Responsible for Tissue Elasticity

Elastin is Responsible for Tissue Elasticity

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Related Experiment Video

Updated: Jun 27, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

[Two cases of papular elastorrhexis].

C Pajot¹, C Le Clec'h, F Hoareau

¹Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 09, France.

Annales De Dermatologie Et De Venereologie

|December 9, 2008

Summary

This summary is machine-generated.

Papular elastorrhexis is a rare skin condition causing asymptomatic papules. One case presented large lesions with mucin deposits, while another developed Hodgkin

Related Experiment Videos

Last Updated: Jun 27, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Area of Science:

Dermatology
Pathology
Genetics

Background:

Papular elastorrhexis is a rare dermatosis.
Characterized by asymptomatic papules on the trunk and upper extremities.
Histology reveals elastic fiber loss/fragmentation and collagen bundle thickening.

Observation:

Case 1: 46-year-old male with 20-year history of asymptomatic papules, some up to 15cm wide, on back and upper limbs.
Histology showed thickened collagen, near-complete dermal elastic fiber loss, fragmentation, and mucin deposits.
Case 2: 34-year-old male with 4-year history of similar papules on back; developed Hodgkin's lymphoma.

Findings:

Two distinct cases of papular elastorrhexis are presented.
The first case featured unusually large lesions and mucin deposits.
The second case was associated with the development of Hodgkin's disease.

Implications:

Highlights the rarity and varied presentations of papular elastorrhexis.
Broadens differential diagnosis to include Buschke-Ollendorff syndrome and other elastic tissue disorders.
Suggests a potential, though unproven, association with hematologic malignancies like Hodgkin's lymphoma.