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Updated: Jun 27, 2026

Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction
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Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction

Published on: September 25, 2017

Ratcheting Myc

Brian W Freie1, Robert N Eisenman

  • 1Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.

Cancer Cell
|December 9, 2008
PubMed

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Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...