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Updated: Jun 27, 2026
03:55
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
[Thyroid carcinoma: from diagnosis to therapy].
Antonio Marrazzo1, Pietra Taormina, Massimo David
1Dipartimento di Oncologia Sperimentale e Applicazioni Cliniche, Università degli Studi di Palermo.
Chirurgia Italiana
|December 10, 2008
Summary
Thyroid cancer affects 25% of patients, with higher risks in those under 30 or over 70 and in males. Thyroid surgery is safe with a low morbidity rate of approximately 2%.
Area of Science:
- Endocrinology
- Surgical Oncology
- Diagnostic Imaging
Context:
- Analysis of 416 thyroid surgery cases (104 malignant, 312 benign) from 1999-2007.
- Evaluation of patient demographics including age and gender distribution for thyroid lesions.
- Assessment of diagnostic modalities: ultrasonography, scintigraphy, and fine needle aspiration cytology (FNAC).
Purpose:
- To determine the incidence and distribution of thyroid cancer versus benign nodules.
- To identify age and gender-specific risk factors for thyroid malignancies.
- To evaluate the diagnostic accuracy and feasibility of various imaging and cytologic techniques.
Summary:
- Thyroid cancer incidence was 25%, with peak rates in patients under 30 (52%) and over 70 (46%). Males exhibited a higher incidence than females.
- Scintigraphy showed low uptake in 47.5% of cancer cases; ultrasonography identified hypoechoic nodules in 41.3%. FNAC detected fibronectin expression in 14.4% of cases.
- Thyroid surgery demonstrated a low morbidity rate (2%), including rare recurrent nerve injury (0.5%) and transient hypocalcemia (6.7%).
Impact:
- Highlights specific age and gender groups at higher risk for thyroid cancer.
- Provides insights into the diagnostic performance of non-invasive methods for thyroid nodules.
- Confirms the safety and low complication rate of surgical intervention for thyroid disease.
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