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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Jun 27, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Functional MR imaging in multiple sclerosis.

Massimo Filippi¹, M A Rocca

¹Neuroimaging Research Unit, Department of Neurology, San Raffaele Scientific Institute and University, Via Olgettina, 60-20132, Milan, Italy. filippi.massimo@hsr.it

Neuroimaging Clinics of North America

|December 10, 2008

Summary

This summary is machine-generated.

Variable recovery mechanisms impact multiple sclerosis (MS) symptom resolution. Brain

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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

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Published on: December 18, 2016

Area of Science:

Neuroscience
Neurology
Medical Imaging

Background:

Multiple sclerosis (MS) involves variable effectiveness in tissue repair and recovery.
Understanding these mechanisms is key to explaining symptom resolution and functional maintenance in MS patients.

Purpose of the Study:

To investigate the role of reparative and recovery mechanisms in multiple sclerosis (MS).
To explore how cortical changes after white matter injury impact clinical outcomes in MS.
To identify factors contributing to the accumulation of fixed neurological deficits in MS.

Main Methods:

Functional magnetic resonance imaging (fMRI) was applied to patients with multiple sclerosis (MS).
Analysis focused on cortical changes following white matter injury.

Main Results:

Functional MR imaging revealed cortical changes subsequent to white matter injury in MS.
These adaptive cortical changes can influence the clinical outcome of MS-related damage.
Failure of cerebral cortex adaptive properties correlates with accumulating neurological deficits in MS.

Conclusions:

The effectiveness of reparative mechanisms varies in multiple sclerosis (MS).
Cortical plasticity plays a role in the clinical presentation and progression of MS.
Exhaustion of adaptive brain functions contributes to irreversible neurological deficits in MS.