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Published on: April 17, 2019
Prepubertal distal longitudinal vaginal folds
Albert Altchek1, Brad Wasserman, Liane Deligdisch
1Department of Obstetrics, Gynecology and Reproductive Science, New York, New York, USA. AlbertAltchek@aol.com
Prepubertal distal longitudinal vaginal folds are common and benign, typically disappearing by puberty. These folds, composed of normal vaginal mucosa, lack a dense fibrous core, allowing them to resolve naturally.
Area of Science:
- Pediatric Gynecology
- Vaginal Anatomy
- Histopathology
Background:
- Prepubertal distal longitudinal vaginal folds are anatomical variations observed in young females.
- Understanding their nature is crucial for accurate diagnosis and to avoid misinterpretation.
Purpose of the Study:
- To provide a detailed description of prepubertal distal longitudinal vaginal folds.
- To elucidate the natural history and resolution of these folds through puberty.
Main Methods:
- Histological examination of fold biopsies.
- Longitudinal follow-up of patients through puberty.
Main Results:
- Histology reveals normal vaginal mucosa over loose fibrous connective tissue, lacking a dense fibrous core.
- The vaginal folds naturally disappear during puberty.
Conclusions:
- Prepubertal distal longitudinal vaginal folds are benign findings.
- Physiologic estrogenic changes during puberty lead to vaginal widening and lengthening, causing the folds to resolve.
- These folds can be mistaken for conditions like vaginal rhabdomyosarcoma or signs of sexual abuse if they extend to the hymen.
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