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Published on: December 28, 2014
Use of imaging in restorative stroke trials
1University of California, Irvine Medical Center, 101 The City Drive South, Building 53 Room 203, Orange, CA 92868-4280, USA. scramer@uci.edu
Abstract:
Restorative therapies aim to improve behavioral outcome after stroke by promoting repair and restoration. Measures of CNS injury and function might be useful to evaluate such therapies in a clinical trial, for example, by optimizing patient selection or treatment dose. These issues are considered in this review, with specific examples provided.
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