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Related Concept Videos

Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
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Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
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Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
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Updated: Jun 27, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

[Aspergillosis].

Tsunehiro Ando1, Atsuko Moriya, Kazutoshi Shibuya

  • 1Department of Infectious Diseases, Japanese Red Cross Medical Center.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 17, 2008
PubMed
Summary

Aspergillosis diagnosis and treatment are challenging. Revised guidelines aim to standardize care for invasive fungal infections, including pulmonary aspergillosis, with new diagnostic methods and antifungal drugs improving strategies.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Clinical Guidelines

Context:

  • Aspergillosis is an opportunistic infection with difficult diagnosis and treatment.
  • Japan's 2007 guidelines for invasive fungal infection aimed to standardize management.
  • Pulmonary aspergillosis diagnosis and treatment require urgent improvement.

Purpose:

  • To outline the diagnostic and therapeutic algorithm from Japan's revised guidelines for invasive fungal infections.
  • To highlight the challenges in diagnosing and treating pulmonary aspergillosis.
  • To discuss the impact of new diagnostic methods and antifungal drugs on aspergillosis management.

Summary:

  • The guidelines categorize infections into 'Proven', 'Clinically documented/Probable', and 'Possible'.

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Last Updated: Jun 27, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

  • Therapy is divided into 'empiric' and 'targeting' approaches.
  • Recent advancements in serological diagnostics and new antifungal agents are transforming treatment strategies for pulmonary aspergillosis.

    • Impact:

    • Standardization of invasive fungal infection management in Japan.
    • Potential for improved early diagnosis and treatment outcomes for aspergillosis.
    • Adaptation of clinical practice due to evolving diagnostic and therapeutic options.