Related Experiment Video
Updated: Jun 27, 2026

Laparoscopic Duodenum-Preserving Pancreatic Head Resection via Inferior Infracolic Approach: A Surgical Approach for Benign Lesions
Published on: February 9, 2024
[Serous microcystic adenoma of the head of the pancreas causing an obstructive jaundice]
Radoje Colović1, Nikica Grubor, Marjan Micev
1Klinicki centar Srbije, Institut za bolesti digestivnog sistema, Beograd, Srbija. marcolov@eunet.yu
Background:
Serous microcystic adenoma is a rare benign tumor of the exocrine pancreas originating from the ductal system and composed of a large number of small cysts covered by cuboid cells, filled with clear serous fluid and separated with fibrocolagenous stroma. Most frequently it appears in women in 7th and 8th decades, in the distal pancreas. It shows a very low malignant potential. In 2/3 of patients symptoms are uncharacteristic and in 1/3 they are absent When localised within the head of the pancreas it rarely causes an obstructive jaundice.
Case Report:
We presented a 61-year-old female patient who for months had had mild and nonspecific abdominal symptoms developing to progressive obstructive jaundice. At surgery we revealed a rather large policystic mass of the head of the pancreas causing not only obstructive jaundice but also a venous stasis by compression and dislocation of the portomesenteric vein. The tumor was removed with pylorus preserving cephalic duodenopancreatectomy (Whipple's procedure modified by Longmire-Traverso). Histology confirmed serous microcystic adenoma of the pancreas. The postoperative recovery was uneventful and preoperative symptoms disappeared.
Conclusion:
Although very rare, serous microcystic adenoma might appear within the head of the pancreas and has to be taken into consideration in differential diagnosis of cystic lesions of the head of the pancreas. Very rarely the tumour might cause obstructive jaundice. Surgical resection, which might be demanding, leads to complete recovery.
Insights
Serous microcystic adenoma, a rare pancreatic tumor, can occur in the pancreatic head, potentially causing obstructive jaundice. Surgical resection offers a complete recovery for this benign condition.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Serous microcystic adenoma (SMA) is a rare, benign pancreatic tumor originating from the exocrine ductal system.
- Characterized by numerous small cysts filled with serous fluid, SMA typically affects women in their 7th and 8th decades, often in the distal pancreas.
- SMA has a very low malignant potential, with symptoms frequently being nonspecific or absent.
Observation:
- A case of a 61-year-old female presenting with progressive obstructive jaundice and nonspecific abdominal symptoms.
- Surgical exploration revealed a large, polycystic mass in the pancreatic head causing obstructive jaundice and portomesenteric vein compression.
- The patient underwent a pylorus-preserving cephalic duodenopancreatectomy (modified Whipple procedure).
Findings:
- Histological examination confirmed the diagnosis of serous microcystic adenoma of the pancreas.
- The patient experienced an uneventful postoperative recovery, with complete resolution of preoperative symptoms.
- The tumor's location in the pancreatic head, though rare, was responsible for the obstructive jaundice and venous stasis.
Implications:
- SMA must be considered in the differential diagnosis of cystic lesions in the pancreatic head.
- While rare, SMA can present with obstructive jaundice, necessitating careful evaluation.
- Surgical resection, although potentially complex, is an effective treatment leading to complete patient recovery.
Related Concept Videos
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology
Jaundice
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include: