[Serous microcystic adenoma of the head of the pancreas causing an obstructive jaundice]

Radoje Colović1, Nikica Grubor, Marjan Micev

  • 1Klinicki centar Srbije, Institut za bolesti digestivnog sistema, Beograd, Srbija. marcolov@eunet.yu

Vojnosanitetski Pregled
|December 17, 2008
PubMed
Abstract

Insights

Serous microcystic adenoma, a rare pancreatic tumor, can occur in the pancreatic head, potentially causing obstructive jaundice. Surgical resection offers a complete recovery for this benign condition.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Serous microcystic adenoma (SMA) is a rare, benign pancreatic tumor originating from the exocrine ductal system.
  • Characterized by numerous small cysts filled with serous fluid, SMA typically affects women in their 7th and 8th decades, often in the distal pancreas.
  • SMA has a very low malignant potential, with symptoms frequently being nonspecific or absent.

Observation:

  • A case of a 61-year-old female presenting with progressive obstructive jaundice and nonspecific abdominal symptoms.
  • Surgical exploration revealed a large, polycystic mass in the pancreatic head causing obstructive jaundice and portomesenteric vein compression.
  • The patient underwent a pylorus-preserving cephalic duodenopancreatectomy (modified Whipple procedure).

Findings:

  • Histological examination confirmed the diagnosis of serous microcystic adenoma of the pancreas.
  • The patient experienced an uneventful postoperative recovery, with complete resolution of preoperative symptoms.
  • The tumor's location in the pancreatic head, though rare, was responsible for the obstructive jaundice and venous stasis.

Implications:

  • SMA must be considered in the differential diagnosis of cystic lesions in the pancreatic head.
  • While rare, SMA can present with obstructive jaundice, necessitating careful evaluation.
  • Surgical resection, although potentially complex, is an effective treatment leading to complete patient recovery.

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