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Published on: February 16, 2018
Recent developments of molecularly imprinted polymer in CEC
Yan-Ping Huang1, Zhao-Sheng Liu, Chao Zheng
1College of Pharmacy, Tianjin Medical University, Tianjin, China.
Electrophoresis
|December 17, 2008
Summary
This review covers advances in molecularly imprinted polymers (MIPs) for capillary electrophoresis (CE) since 2006. It details new MIP preparation techniques for CE applications, including covalent approaches and monolithic columns.
Area of Science:
- Analytical Chemistry
- Polymer Science
- Separation Science
Background:
- Capillary Electrophoresis (CE) is a powerful separation technique.
- Molecularly Imprinted Polymers (MIPs) offer tailored recognition capabilities.
- Integrating MIPs into CE enhances selectivity for specific analytes.
Purpose of the Study:
- To review developments in MIPs for CE since August 2006.
- To discuss novel MIP preparation techniques applicable to CE.
- To explore future research directions in MIP-based CE.
Main Methods:
- Review of literature on MIP preparation for CE.
- Discussion of techniques including covalent approaches (Schiff base formation).
- Exploration of miniemulsion polymerization and non-hydrolytic sol-gel methods.
- Analysis of MIP-derivatized silica monolithic columns for CE.
Main Results:
- Significant advancements in MIP preparation for CE have been made.
- Various novel techniques enable the creation of selective MIP-based CE platforms.
- MIP-derivatized monolithic columns show promise for efficient separations.
Conclusions:
- MIPs represent a key development for enhancing CE selectivity.
- Continued innovation in MIP synthesis will further advance CE applications.
- Future research should focus on novel materials and integrated systems.
