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Updated: Jun 27, 2026

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
Neurologic and vascular injuries associated with knee ligament injuries
Michael E Johnson1, Lynanne Foster, Jesse C DeLee
1University of Texas Health Science Center at San Antonio, Department of Orthopaedics, San Antonio, TX 78229, USA. johnsonm3@uthscsa.edu
Background:
Multiple ligament knee injuries are commonly associated with neurovascular complications such as popliteal artery, common peroneal nerve, and tibial nerve injuries.
Hypothesis:
While the importance of identifying these complications in association with bicruciate and triligamentous injuries has been well established, it is important to recognize that any biligamentous and some single ligament knee injuries present with neurological and vascular complications as well.
Study Design:
Literature review.
Conclusion:
Popliteal artery injuries require immediate intervention to help prevent limb loss. Peroneal and tibial nerve injuries can be a significant cause of morbidity and, therefore, require an understanding of their natural history, anatomy, and pathophysiologic implications to maximize functionality.
Clinical Relevance:
This review explores the types, mechanisms, and classifications of common neurovascular complications of knee ligament injuries, discusses their diagnosis, and reviews the therapeutic options available to optimize patient outcomes.
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