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Inflammation and stem cells in gastrointestinal carcinogenesis

Michael Quante1, Timothy Cragin Wang

  • 1Division of Digestive and Liver Diseases, Columbia University Medical Center, Irving Cancer Research Center, New York, New York, USA.

Physiology (Bethesda, Md.)
|December 17, 2008
PubMed
Summary

Chronic inflammation drives gastrointestinal cancer by altering the stem cell niche, influencing tumor initiation and progression. This review explores the connection between inflammation, stem cells, and cancer stem cells in this process.

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