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Nanocarriers for systemic and mucosal vaccine delivery
Aliasgar Shahiwala1, Tushar K Vyas, Mansoor M Amiji
1Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.
Recent Patents on Drug Delivery & Formulation
|December 17, 2008
Summary
Nanotechnology is revolutionizing vaccine development, offering targeted delivery and enhanced immune responses for infectious diseases. This review explores patented nanocarrier-based vaccine innovations for improved immunization strategies.
Area of Science:
- Vaccinology
- Nanotechnology
- Immunology
Background:
- Vaccine research has advanced significantly, leading to numerous disease-specific vaccines.
- Improving vaccine effectiveness and optimizing immunization are key research areas.
- Nanotechnology offers novel nanocarrier-based vaccines for targeted delivery and cellular immune response.
Purpose of the Study:
- To review patented nanocarrier-based vaccine formulations and delivery systems.
- To identify strategic approaches for infectious disease prevention using nanotechnology.
- To examine US patent literature for relevant nanovaccine inventions.
Main Methods:
- Systematic review of United States patent literature.
- Focus on inventions related to nanocarrier-based vaccine formulations.
- Analysis of patented delivery systems for infectious disease prevention.
Main Results:
- Identification of patented nanocarrier systems for vaccine development.
- Highlighting strategies for improved targeting and cellular immune response.
- Examination of patented routes for vaccine administration to induce mucosal and systemic immunity.
Conclusions:
- Nanocarrier-based vaccines represent a significant advancement in immunization.
- Judicious selection of nanocarriers and antigens can optimize vaccine efficacy.
- Patented innovations demonstrate the strategic potential of nanovaccines for infectious disease prevention.
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