Related Experiment Video
Updated: Jun 27, 2026
10:27
The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight
Published on: October 11, 2016
Innovations in coating technology.
Sharareh S Behzadi1, Stefan Toegel, Helmut Viernstein
1Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Vienna, Austria. sharareh.salar-behzadi@univie.ac.at
Recent Patents on Drug Delivery & Formulation
|December 17, 2008
Summary
Pharmaceutical coating enhances drug delivery through improved taste, odor masking, and controlled release. Recent patents focus on advanced manufacturing techniques and analytical methods for quality control in drug formulation.
Area of Science:
- Pharmaceutical Technology
- Drug Delivery Systems
- Process Engineering
Background:
- Pharmaceutical coating is a long-standing technique with evolving applications, from basic taste masking to sophisticated controlled drug release.
- Modern pharmaceutical manufacturing demands reproducible and controllable coating processes to meet high product quality standards.
- Regulatory bodies like the FDA emphasize Quality by Design (QbD), necessitating robust analytical methods for process understanding and control.
Purpose of the Study:
- To review recent patents on pharmaceutical coating technology, focusing on advancements in processing and analytical methods.
- To provide an overview of established and novel coating procedures, including pan and fluidized bed coating.
- To detail the application of analytical tools for managing and controlling pharmaceutical coating processes.
Main Methods:
- Review of recent patents related to pharmaceutical coating technologies.
- Categorization of coating methods into pan coating (inclined, horizontal, vertical axes) and fluidized bed coating (fluidized and spouted beds).
- Discussion of continuous processing techniques, spraying system improvements, and analytical methods for process analysis and control.
Main Results:
- Identification of key areas for improvement in coating methods: particle movement, spraying systems, and air/energy transport.
- Emphasis on achieving homogeneous coating material distribution and enhanced drying efficiency for superior product quality.
- Detailed review of analytical techniques for real-time monitoring, analysis, and management of coating processes.
Conclusions:
- Advancements in pharmaceutical coating technologies are driven by the need for precise control over drug release and product quality.
- The integration of Quality by Design principles necessitates sophisticated analytical tools for process understanding and optimization.
- Continuous innovation in coating equipment and analytical methodologies is crucial for meeting the demands of modern drug formulation.
