BMI and lipid levels in Mexican American children diagnosed with type 2 diabetes
Linda Fortmeier-Saucier1, Carol Savrin, Marjorie Heinzer
1Case Western Reserve University, Cleveland, Ohio, USA. fortmeiers@uthscsa.edu
Insights
Obese Mexican American children with type 2 diabetes often have abnormal cholesterol and triglyceride levels. Increased body mass index (BMI) correlates with higher risks of these abnormal lipid values.
Area of Science:
- Pediatric Endocrinology
- Cardiovascular Health
- Metabolic Disorders
Background:
- Childhood obesity is a growing epidemic linked to rising type 2 diabetes rates.
- Previous studies show a strong link between obesity and abnormal lipids in non-diabetic children of other ethnicities.
- The lipid profiles of Mexican American children with type 2 diabetes remained understudied.
Purpose of the Study:
- To investigate the association between body mass index (BMI)-defined obesity and lipid profiles in Mexican American children diagnosed with type 2 diabetes.
- To identify specific lipid abnormalities prevalent in this pediatric population.
Main Methods:
- Retrospective review of medical records from a Southwest military medical center.
- Analysis of lipid values (total cholesterol, HDL, LDL, triglycerides) and BMI in 49 Mexican American children with type 2 diabetes.
- Statistical analysis using descriptive and logistic regression.
Main Results:
- 90% of the study participants were classified as obese.
- 75% of children exhibited two or more abnormal lipid values.
- Statistically significant associations were found between obesity and abnormal total cholesterol, HDL, and triglyceride levels.
Conclusions:
- Mexican American children with type 2 diabetes demonstrate significant links between obesity (BMI) and abnormal lipid levels.
- Higher BMI directly correlates with an increased likelihood of abnormal total cholesterol, triglycerides, and HDL.
- Findings contribute to understanding cardiovascular disease risk markers in this pediatric population.
Purpose:
The purpose of this study was to determine potential associations between obesity as measured by body mass index (BMI) and lipid values in Mexican American (MA) children diagnosed with type 2 diabetes.
Background:
Obesity in children is considered to be an emerging epidemic that is accompanied by an increase in prevalence of type 2 diabetes. Literature shows that there is a direct and strong relationship between abnormal lipid levels and obesity in Caucasian and African American children without type 2 diabetes. However, it was unknown whether Mexican American children diagnosed with type 2 diabetes have abnormal lipid levels.
Method:
A retrospective medical-record review was conducted on paediatric patients who received medical care from a military medical centre in the Southwest region of the United States. A convenience sample of records was used to study the relationship between obesity as measured by BMI and lipid levels in 49 Mexican American children diagnosed with type 2 diabetes. Total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides (TG), and BMI were reviewed. Data were analysed using descriptive and logistic regression statistics.
Findings:
Ninety percent of the sample was obese and 75% had two or more abnormal lipid values. Abnormal levels of total cholesterol, HDL, and triglycerides were found to be statistically significant.
Conclusions:
The main findings indicate that MA children diagnosed with type 2 diabetes had significant associations between obesity as measured by BMI and abnormal total cholesterol, HDL, and triglyceride levels. As the BMI increased, the probability of abnormal total cholesterol and triglyceride levels increased. Similarly, as the BMI increased, the probability of abnormal HDL values increased. Mexican American children in this study had obesity levels similar to those in a study by the National Center for Health Statistics. In this study a step has been taken toward understanding a physiologic marker for cardiovascular disease in children.
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