Related Experiment Video
Updated: Jun 27, 2026

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
Published on: March 13, 2012
Post-radiation sciatic neuropathy: a case report and review of the literature
Panagiotis D Gikas1, Sammy A Hanna, Will Aston
1Bone Tumour Unit, Royal National Orthopaedics Hospital, Middlesex, UK. pdgikas@doctors.org.uk
Background:
Post-radiation peripheral neuropathy has been reported in brachial and cervical plexuses and the femoral nerve.
Case Presentation:
We describe a patient who developed post-radiation sciatic neuropathy after approximately 3 years and discuss the pathophysiology, clinical course and treatment options available for the deleterious effects of radiation to peripheral nerves.
Conclusion:
This is the first case of post-radiation involvement of the sciatic nerve reported in the literature.
