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Myokymia in axonal disorders
1From the Department of Neurology, University of Iowa, Iowa City, IA.
Journal of Clinical Neuromuscular Disease
|December 17, 2008
Summary
Myokymic discharges, typically linked to demyelinating diseases, were observed in axonal disorders in five patients. This study includes a novel case of myokymia following Botox injection.
Area of Science:
- Neurology
- Neurophysiology
Background:
- Myokymic discharges represent rhythmic motor unit activity.
- Myokymia is predominantly associated with demyelinating neuropathies.
Purpose of the Study:
- To investigate the occurrence of myokymia in axonal disorders.
- To report a unique case of myokymia after Botox injection.
Main Methods:
- Clinical case series.
- Electromyography (EMG) findings in five patients.
Main Results:
- Myokymia was identified in five patients with axonal disorders.
- One patient developed myokymia after receiving Botox injections.
Conclusions:
- Myokymia can manifest in axonal disorders, challenging the traditional association with demyelination.
- Botox-induced myokymia is a previously unreported phenomenon.
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