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Related Experiment Video

Updated: Jun 27, 2026

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties

Published on: February 19, 2020

Myokymia in axonal disorders.

Praful Kelkar¹, Jun Kimura

¹From the Department of Neurology, University of Iowa, Iowa City, IA.

Journal of Clinical Neuromuscular Disease

|December 17, 2008

Summary

This summary is machine-generated.

Myokymic discharges, typically linked to demyelinating diseases, were observed in axonal disorders in five patients. This study includes a novel case of myokymia following Botox injection.

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Axonal Transport of Organelles in Motor Neuron Cultures using Microfluidic Chambers System

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Published on: May 5, 2020

Area of Science:

Neurology
Neurophysiology

Background:

Myokymic discharges represent rhythmic motor unit activity.
Myokymia is predominantly associated with demyelinating neuropathies.

Purpose of the Study:

To investigate the occurrence of myokymia in axonal disorders.
To report a unique case of myokymia after Botox injection.

Main Methods:

Clinical case series.
Electromyography (EMG) findings in five patients.

Main Results:

Myokymia was identified in five patients with axonal disorders.
One patient developed myokymia after receiving Botox injections.

Conclusions:

Myokymia can manifest in axonal disorders, challenging the traditional association with demyelination.
Botox-induced myokymia is a previously unreported phenomenon.