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Updated: Jun 27, 2026

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
Combining synaptic and cellular resonance in a feed-forward neuronal network
Jonathan D Drover1, Vahid Tohidi, Amitabha Bose
1Department of Mathematical Sciences, New Jersey Insitutute of Technology, Newark NJ 07102.
Abstract:
We derive a mathematical theory to explain the subthreshold resonance response of a neuron to synaptic input. The theory shows how a neuron combines information from its intrinsic resonant properties with those of the synapse to determine the neuron's generalized resonance response. Our results show that the maximal response of a postsynaptic neuron can lie between the preferred intrinsic frequency of the neuron and the synaptic resonance frequency. We compare our theoretical results to parallel findings on experiments of the crab pyloric central pattern generator.
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