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Updated: Jun 27, 2026

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
08:04

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling

Published on: October 8, 2019

Early interrogation and recognition of DNA sequence by indirect readout.

Elizabeth J Little1, Andrea C Babic, Nancy C Horton

  • 1Department of Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ 85721, USA.

Structure (London, England : 1993)
|December 17, 2008
PubMed
Summary

Proteins find specific DNA sequences through direct or indirect readout. A mutant HincII enzyme, lacking direct DNA contact, surprisingly retained sequence specificity, suggesting indirect readout plays a key role.

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