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Lymphatic Vessels and Lymph Transport

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A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
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Published on: November 2, 2019

Pelvic lymphedema: truth or fiction?

Alberto Vannelli1, Luigi Battaglia, Elia Poiasina

  • 1Division of General Surgery B Foundation IRCCS "National Institute of Tumour", Lymphology La Statale University, Milan, Via Venezian 1, 20133 Milan, Italy. a.vannelli@tiscalinet.it

Medical Hypotheses
|December 17, 2008
PubMed
Summary
This summary is machine-generated.

Pelvic disorders after oncological surgery may stem from pelvic lymphedema, a condition affecting lymphatic vessels. Understanding this link is crucial for developing effective rehabilitation therapies for affected patients.

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Area of Science:

  • Oncology
  • Surgical Pathology
  • Rehabilitation Medicine

Background:

  • Radical pelvic surgery for oncological diseases frequently leads to pelvic disorders.
  • These post-surgical pelvic disorders manifest as fatty tissue hypertrophy and fibrosis, independent of specific surgical techniques or adjuvant therapies.
  • The underlying cause of these prevalent pelvic floor and perineum dysfunctions remains largely unidentified.

Purpose of the Study:

  • To investigate the potential role of pelvic lymphedema in the development of post-surgical pelvic disorders.
  • To explore the connection between lymphadenectomy and the onset of pelvic floor and perineum dysfunction.
  • To identify pelvic lymphedema as a key factor in understanding and treating post-pelvic surgery disorders.

Main Methods:

  • Clinical observation of patients undergoing radical pelvic surgery.
  • Assessment of pelvic floor and perineum function post-operation.
  • Evaluation of lymphatic system involvement in pelvic pathologies.
  • Analysis of symptoms including fatty tissue hypertrophy, fibrosis, and functional chronic disorders.

Main Results:

  • Pelvic disorders post-oncological surgery are common and persistent without rehabilitation.
  • Lymphedema, characterized by fluid retention, hypertrophy, and fibrosis, is a recognized pathological condition.
  • A hypothesis is proposed that lymphadenectomy contributes to localized pelvic lymphedema, causing perineum and pelvic floor disorders.

Conclusions:

  • Pelvic lymphedema, potentially developing after lymphadenectomy, is a significant factor in post-surgical pelvic floor and perineum dysfunction.
  • The lymphatic system's role in pelvic floor and perineum pathology is clinically evident.
  • Further study of pelvic lymphedema is essential for optimizing therapeutic strategies for post-surgical pelvic disorders.