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Pregabalin has opioid-sparing effects following augmentation mammaplasty
Bruce M Freedman1, Elizabeth O'Hara
1BFreedman58@aol.com
Aesthetic Surgery Journal
|December 17, 2008
Summary
Adding pregabalin to pain management significantly reduced narcotic use and pain after augmentation mammaplasty. This anticonvulsant offers a safe alternative for managing postoperative discomfort and nausea.
Area of Science:
- Anesthesiology
- Plastic Surgery
- Pain Management
Background:
- Growing concern over narcotic use in surgical patients.
- Need for effective non-narcotic postoperative pain management strategies.
Purpose of the Study:
- To evaluate the efficacy of pregabalin as an adjunct analgesic in augmentation mammaplasty.
- To determine if pregabalin reduces postoperative narcotic consumption and pain scores.
Main Methods:
- Randomized controlled trial with 80 patients undergoing augmentation mammaplasty.
- Group A received hydrocodone as needed; Group B received hydrocodone plus pregabalin.
- Pain, narcotic use, and nausea were assessed postoperatively.
Main Results:
- Pregabalin group (Group B) showed a 70% reduction in hydrocodone use compared to Group A.
- Average pain scores were significantly lower in Group B (3.4 vs. 5.3).
- Group B reported a 46% reduction in nausea and fewer side effects.
Conclusions:
- Perioperative pregabalin significantly decreases narcotic requirements after augmentation mammaplasty.
- Pregabalin effectively reduces postoperative pain and nausea with a favorable safety profile.
- Consider pregabalin as a safe and effective component of multimodal analgesia.
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