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Updated: Jun 27, 2026
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Generation of Stable Transgenic C. elegans Using Microinjection
Published on: August 15, 2008
Germline transformation of Caenorhabditis elegans by injection
Pavan Kadandale1, Indrani Chatterjee, Andrew Singson
1Waksman Institute, Rutgers University, Piscataway, NJ, USA.
Methods in Molecular Biology (Clifton, N.J.)
|December 17, 2008
Abstract:
Microinjection is a commonly used technique for DNA transformation in Caenorhabditis elegans. It is a powerful tool that links genetic and molecular analysis to phenotypic analysis. In this chapter we shall provide an overview of microinjection for germline transformation in worms. Our discussion will emphasize C. elegans reproductive biology, applications and protocols for carrying out microinjection in order to successfully obtain transgenic worms.
