Related Experiment Video
Updated: Jun 27, 2026
Murine Model of Epicutaneously-Induced Immunomodulation
Published on: June 24, 2025
[Immunomodulatory effect of Indian ginseng root extract on immunodeficiency mice]
1Food Science College, Southwest University, Chongqing 400716, China. zhoucaiqiong@swu.edu.cn
Objective:
To investigate the immunoregulation action of Indian ginseng root extract (IRRE) in immunodeficiency mice.
Method:
Immunodeficiency mice were fed IRRE with doses of 5, 2.5, 0.85 g x kg(-1) for 15 days before their immune function were observed.
Result:
IRRE could relieve retarded growth and viscera index drop of mice induced by CP, could heighten the response of delayed hypersensitivity and the amount of antibody in serum. The proliferation of ConA-induced mitogenic response for spleen lymphocyte were also increased, compared with the CP group (P < 0.05). IRRE could enhance the content of marrow DNA and NO of serum with no change of acid phosphatase and alkalinity phosphatase.
Conclusion:
IRRE could enhance the phagocytosis of celiac macrophage, protect the spleen from damage and improve marrow inhibition in immunodeficiency mice.
