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Related Concept Videos

Transgenic Organisms00:53

Transgenic Organisms

Overview
Transgenic Organisms00:53

Transgenic Organisms

Overview
Transgenic Plants02:50

Transgenic Plants

Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
Transduction01:16

Transduction

Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome are...
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.

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Manipulation of Gene Function in Mexican Cavefish
07:01

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Published on: April 22, 2019

Altering nutrient utilization in animals through transgenesis.

K A Ward1

  • 1Commonwealth Scientific and Industrial Research Organization Animal Production, Locked Bag 1, Delivery Center, Blacktown, NSW 2148, Australia. kevin@nugget.prospect.anprod.csiro.au

Nutrition Research Reviews
|December 18, 2008
PubMed
Summary
This summary is machine-generated.

Genetic modification of domestic animals offers a faster route to improved productivity and nutrient utilization compared to traditional breeding. This technology holds promise for increasing food supply but faces challenges in gene integration and expression.

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Area of Science:

  • Agricultural Science
  • Biotechnology
  • Animal Genetics

Background:

  • Increasing global population necessitates enhanced domestic animal productivity.
  • Current genetic selection methods for improving animal productivity are slow.
  • Recombinant DNA technology offers a rapid alternative for genetic improvement.

Purpose of the Study:

  • To review the application of genome modification in domestic animals for enhanced nutrient utilization and productivity.
  • To discuss progress and challenges in genetic engineering for animal agriculture.

Main Methods:

  • Review of existing literature on recombinant DNA technology in domestic animals.
  • Focus on two key areas: growth hormone modification and introduction of novel biochemical pathways.
  • Examination of gene integration and expression in modified animal genomes.

Main Results:

  • Modification of growth hormone levels shows potential for field trials.
  • Introduction of a cysteine biosynthetic pathway demonstrates the possibilities and challenges of novel pathway integration.
  • Research highlights the complexities of foreign gene expression within existing animal biochemistry.

Conclusions:

  • Genome modification technology is a powerful tool for advancing animal productivity and nutrient utilization.
  • While promising, challenges remain in the practical application and integration of foreign genes.
  • Continued research is essential to overcome technical hurdles for commercial viability.