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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Reactions02:06

Allergic Reactions

Overview
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

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Related Experiment Video

Updated: Jun 27, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

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Published on: September 14, 2018

[Food-dependent exercise-induced anaphylaxis].

Bjarne Nordstrøm Kjaer1, Lars Christian Laursen

  • 1Fuglefaengervej 15, 2. tv., DK-2400 København NV. bjarnenk@ofir.dk

Ugeskrift for Laeger
|December 18, 2008
PubMed
Summary
This summary is machine-generated.

Food-dependent exercise-induced anaphylaxis (FDEIA) is a rare food allergy triggered by exercise after eating specific foods, like wheat. Avoiding the trigger food for four hours before exercise prevents severe allergic reactions.

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Area of Science:

  • Allergy and Immunology
  • Exercise Physiology
  • Gastroenterology

Background:

  • Food-dependent exercise-induced anaphylaxis (FDEIA) is a rare but potentially severe allergic reaction.
  • It occurs when specific foods are consumed before physical activity.
  • Wheat is a common trigger, but other foods can also cause FDEIA.

Observation:

  • Symptoms include hives, swelling, asthma, and airway obstruction.
  • Severe cases can lead to dangerously low blood pressure (hypotension) and shock.
  • Anaphylaxis only occurs when both food intake and exercise coincide.

Findings:

  • Consuming trigger foods within four hours before exercise can initiate FDEIA.
  • Avoiding the causative food for at least four hours prior to exercise effectively prevents reactions.
  • FDEIA is often diagnosed late due to its infrequent occurrence.

Implications:

  • Early diagnosis and management are crucial for preventing severe outcomes.
  • Patient education on trigger foods and pre-exercise dietary timing is vital.
  • Further research into FDEIA mechanisms may improve diagnostic and therapeutic strategies.